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Thats the thing these are OBX headers each brand varies for fitment. I have a 4 inch lift in the front so I do have more drive shaft clearance than a stock 4wd.
The frames are similar with the 4wd actually having no crossmenber under the motor.
I can imagine that they would quite possibly clear Im just looking for any ideas and real life situations.
I would think the 2WD header would be pointed straight at the transfer case. It's a tight clearance with the C6, with just 1/2" space between the collector and the shift arm.