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Too many factors (boost levels, oil in the intake pipes, tightness of boot clamps, engine duty cycle, etc etc) to be able to make general life statements. I'd say if they're not mushy or torn, they're fine.
I inspect mine when performing service on the truck. If they look free of oil and aren’t damaged I move to the next item. Depending on the quality of the boot, it should last a long time.
Rezvani's Latest Post-Apocalyptic Monster Is a Ford F-150 Raptor Underneath
Slideshow: Called the Fortress, the 850-horsepower pickup combines Raptor underpinnings with military-inspired features, survival equipment, and a starting price of $285,000.