What can be wrong?

 

If the truck is locked the tailgate will also be locked. Do the doors open?

 

None of the button work tail gate,fob,inside cab.I see that the tail light turn on and off when I push the button.

 

If it's a higher trim truck with release, push the tailgate in at the same time while releasing. Then check your rubber bump stops and make sure they are facing the correct way. They will bind the tailgate and cause a no release.

 

I just had my actuator replaced last weekend