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I have been under my'14 E350 motorhome 3 times tracing the fuel lines and have yet to find the fuel filter anywhere under it. It has a 55 gallon tank and the v10 engine. Someone said in passing it might be in the tank but I thought that would just be the sock-type strainer most vehicles have. Has to be a replaceable filter somewhere more accessible than in a 55 gal. tank in a MH getting 9 MPG. Thanks
They dropped the external fuel filters from the E series in around 2010 as far as I know. So it quite possibly only has the one in the tank and you don't change it.
I have a couple 2010 and 2011 4.6L vans that have pumped somewhere between 45,000 and 50,000 gallons of gas each without any fuel system problems and the fuel pumps are lasting longer. I have two whippersnapper 2013 5.4Ls with around 15,000 gallons pumped each and no problems. So getting rid of the external filters was a good move IMHO.