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I just did tuneup on 2005 Ford Escape 3.0 V.6 four wheel drive. Changed the spark plughs and wireset. Did not change the ginition coil. When the engine run and heat up there is a skipping sound like the vehicle is loosing power.
These vehicles have a Coil on Plug system so if you changed the 'wires' you had to have changed the ignition coil(s).
My first guess would be wires plugged into the wrong coil. But that should cause you to feel a mis right away.
Next would be a bad gap on one of the plugs or a torn boot on a coil.
Are you getting a check engine light? If so have it read and they can tell you which cylinder(s) it is that is causing the issue.
There isn't an "ignition coil" in the Escape engine. Each spark plug has its own coil pack, so you would of had to change 6 coil packs to change the "ignition coil".