First excursion system
Just make sure that you are using the proper gauge wiring for your power amplifiers, give them GOOD grounds, and ensure decent airflow for cooling.
As for running your wires...I always try to keep my power wire runs as far away from my signal wires (RCA) for as long as I can in any installation. Ex.- If I run my power wire down the Driver's side, I'd keep my RCAs on the passenger side (and away from other wires if possible) until it was necessary for the run to approach the amp. Then, I'd run a multiconductor cable from the head unit area to the amp for the door/dash/whatever speakers. Unless you are going with a huge power amplifier you can connect directly to the factory harness and be just fine.
As far as sound deadening goes...if your budget allows (and you're pulling the vehicle to bare floors) any amount you install will be an improvement. My rule of thumb was that outside sounds were best dampened from the bottom up. Floors, wheelwells, and footwells first. Then doors, hatches, and gates. After that roof skins and hoodliners for the ultimate 'tomb-like' ride.
I've had my truck down to the sheet metal and the only place that can fit a small amp is behind the left quarter panel, unless you dont have rear air. Other than that it's under the seats. For such a big truck there is there is absolutely no space for storage. Had to pull both rear seats and build a false floor for storage and sleeping area on camping trips.
I would suggest a good set of separates with a passive cross over. I run my tweeters in the sails with little issues at all. Drivers side is direct and well focused. Passenger side, not so much. Another thing you can look at is the newer 2009+ superdutys. The sail cups on these will fit older superdutys and Excursions. They have the tweeter up higher to allow the sound to better get over the dash.



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