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Look in the tech articles section. There is a post there that covers this and it is a quote from the Ford service manual.
Tips,
1. DO NOT try to do it from under the hood. There should be a sticker on the A/C box under the hood telling you this is the wrong thing to do. The heater core is serviced from under the dash inside the cab.
2. Following the instructions in the tech articles section you will not need to opent the A/C system or recharge it if the charge is good.
3. The procedure will take you between 2-4 hours.
4. Dang this same question comes up a LOT! (last one was about 4 days ago.)
Did mine about 3 weeks ago on my 77 F250.It kinda sucked for sure.I guess there is supposed to be a way to do it without disconnecting any AC lines.But I went ahead and unhooked the AC lines right where they enter the box on the firewall.It was the only way I could pull the AC evaporater coil far enough out on the inside of the cab, to get the heater core out.I looked under the dash and just didn't figure I wanted to take out any more ductwork and such.My way was probably not the best,but it just worked out easier for me.Took out the glove box, and the ductwork that goes to the far passenger side vent though.Replaced the blower motor while I was at it.Everything works good, and now I have nice warm heat in the ole pickem up.
One thing I will mention is, when you get the old core out, be sure and save the foam rubber that surrounds it.Just take your time and work it off slowly.Then stick it on your new one with some weatherstrip adhesive.Because unless yours is different... my new one didn't come with the rubber gasket.
I used a cargo strap w/ the little rachet gizmo to get the A/C out of the way. hooked one end to the drivers side shoulder belt mount, and ran it through the glove box to the passenger side of the A/C condenser. I took off all of the attachment points for the A/C hoses to get as much movement as possible. It didn't give me TONS of room, but I was able to get the job done without disconnecting anything in the A/C (I do no know the first thing about working on A/C so it was the only safe way for me to do this job. It took me about 6 hours, but I took my time.
I've done this procedure twice. Once for the heater core and once for the blower motor (Hint, If you're going to do one on a 30 year old truck you might want to consider the other while your in there!!). Without looking at the procedure in the tech articles section (which is the procedure I used) there is a bracket that holds the A/C hoses to the fire wall. With that bracket disconnected from the firewall you can move the A/C condenser out of the way. The Hoses slide into the A/C-heater box to allow this. There may also be a bracket on the outside of the box that when removed makes the hole bigger. Check out the dang procedure! It's all you need.
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