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i would willing to bet the vast majority of the people that switched to that size tire have done so on the stock 16x7 rims. take a look at my gallery if you want to know how they look on the stock rims.
I've ran 295/75/16's BF All-Terrains for a year on my stock rims prior to lifting with no issues. I don't do any off roading. Street use only. There's a pic in my gallery with the truck before I lifted it.
i had 285/75R16s on my stock rims, and they would rub a little off road and they'd rub the inner fender liner on full-lock turns, but they worked great and made the truck look alot more like a 4x4 truck.
In the winter I run 285/75/16 mud & snows with studs (siped too) on stock rims with no problems on my 03 250 CC 6.0. You can hear the studded tires from about two blocks away
Rezvani's Latest Post-Apocalyptic Monster Is a Ford F-150 Raptor Underneath
Slideshow: Called the Fortress, the 850-horsepower pickup combines Raptor underpinnings with military-inspired features, survival equipment, and a starting price of $285,000.