I usually set my tire pressure by what's printed on the tire sidewall. checking the door sticker it says "Front AT 345 kpa/50 PSI COLD" and" Rear AT 414 kpa/60 PSI COLD"
What does that mean in English. My tire sidewall says 80 psi when cold.

 

The sidewall is stating the max rated pressure. The door sticker is Ford's recommended pressure for all around general use. Lower pressure = smoother ride. Max pressure for max load capacity of the tire.

 

Remember this:

Firestone Wilderness tires used on Explorers in the 90's didn't have problems and weren't considered bad tires until Ford decided that they needed to be run [basically] flat to make the ride nicer. If the sidewall pressure was used then there would be no problems.

You CANNOT run the load listed on the tire sidewall at Ford's recommended inflation pressure. The maximum tire load comes at the listed sidewall pressure. The pickup's GVWR (front and rear) aren't based on the maximum sidewall pressure though.

 

Based on my load range E tires and hauling my 5th wheel cross country at a GCVW of 18,000 - 20,0000 lbs 90% of the time, I inflate my tires to the following.

Front - 60 PSI
Rear - 70 PSI

I have found this to be a suitable inflation rate based on the tire manufacturer listing of inflation PSI based on actual weight of the vehicle. I would recommend you check your tires manufacturer suggested inflation based on the axle weight and take into consideration your payload or towing weight as well.

 

Verbal Rep to Cleatus...you are exactly right on the Firestone bunch of crap. The issue is running the happy medium between what you need as far as load capacity and spinal decompression!

 

If empty a lot I run 70-72 front and 70 rear, loaded I bump to 80 rear, on my old crappy plow truck it is 80 front and back.
I like my front a bit more inflated then some, but I drive really twisty turny mountain roads and soft side walls make for feeling like on a boat.

 

talking tire pressure is akin to talking politics at politics, most have no real idea what is going on but come hell or high water their their way is correct.

from an inflation and load perspective here is what your tire size and pressure can support.
https://www.toyotires.com/media/3729...s_20200723.pdf

first thing you will see is if you run the stock 265/75-16 at max sidewall psi of 80 it will support 3415 lbs or 13,660 pounds all 4 tires
in other words about 30% over inflated.

then again, despite working for a few tire manufactures doing development and testing I know nothing.

 

Maybe some of us run 80 cause we may be a tiny bit overloaded....🙉
I simply go by what handles and wears well for my area, loads and conditions.
There is no one psi fits all.

 

I run unloaded most of the time and have found if I run 70 or higher my tires wear faster in the middle. my happy place for even wear across the tire is about 65 front and 60 in the rear. If I hook up the trailer with the tractor I'll bump the rears up. Goodrich All-Terrain T/A KO2s

 

Empty I run 50ish front and 60ish rear. Which is too high in rear for comfort sake but gives me leeway to chuck something in the bed worry free. I'm not a stickler on tire pressures, I just look at them and adjust if it looks bad.

With 5er trailer I ran 60 front and 80 rear. And adjust the shocks. Need max air for that duty!

As me mates said above, many variables to consider, YMMV.

 

For me, my truck, my driving style, my lack of load-carrying or towing, and my tires, I typically run around 60 psig up front and around 50-53 psig in the rear. I get full life out of my tires and keep an even tread wear pattern through the tires' life.

To achieve the above, I simply use the "dust print test" and tire edge condition (dry roads required for my "test").

Slowly pull into my parking space at work, get out, and look at where the "dusty" part of the dirt is sticking to the tread surface.

If the dust "print" is barely inside the edge of the corner (within 1/4") and I'm not seeing a rolled tread corner, I'm good, and I don't even check the pressure.
If I see too much clean rubber near the edge, there is too much pressure, and I bleed out a few pounds and re-observe my dust print at the next stop.
If I see dust all the way to the tread corner and there is some corner rounding, I run back over to Costco and get a little pressure boost to MAX pressure, and then adjust back down bit by bit until I get the right dust print again.

Some people will argue the point, but my experience in running nitrogen in my tires is that I maintain a more even pressure condition and almost never have to top off my tire pressures from the time I get them installed until I swap them out for new ones (and I almost never rotate the tires or get them rebalanced). I also keep my steering and suspension hardware in good shape.