You may or may not want to relieve the fuel pressure in the rail by either disconnecting a fuel line or the shreader valve at the front of the fuel rail. Simply remove the vacuum line from the FPR then its 3 small allan screws that hold it on.

Straight forward on a truck, but IDK about a van. I would assume you would have to get to it from the dog house.

 

Sounds straightforward, but those 3 bolts go into the fuel rail mount from underneath. So if you have small hands and a small ratcheting driver, you can do the replacement without removing anything else. Otherwise, you may have to at least loosen the fuel rail from the manifold to get better access. On mine, the regulator use allen head bolts, so I used a small bit with my ratcheting tool.