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There is an inline filter located on the inside of the frame rail. It should be sticking out about halfway in front of the front fuel tank.
Ford used several different style of quick disconnect fittings. If you have small plastic tabs sticking out of the fittings they can be pulled out and the lines removed. If there are none, you have the spring-clip type. It takes a special tool that slides down inside the coupler to push the teeth of the spring clip back to allow it to be pulled free. It's usually stuck good too, and the tight location doesn't help any. Which ever style you have make sure you get new clips the old ones usually get mangled. The spring clip type uses two sizes 10mm and 13mm. Get both and return the ones you don't need.
Make sure you relieve the fuel pressure before removing that filter or you're going to get a gasoline shower. It comes out fast and strong. Pressure can be relieved at the schrader valve on the fuel rail. It looks just like a tire valve and is almost out of sight towards the back of the motor.
If you don't want to pull the passenger kick panel to trip the inertia switch, you can unplug the fuel pump from under the truck near the tank. It's a 4-pin white connector. Whichever you do, just crank the truck a few times so it bleeds the pressure off thru the injectors, and you won't get sprayed.
The filter is inside the L frame rail under the driver's seat, and you need the garter spring tools to remove it. ~$8 at CarQuest for 5 sizes.
You could also just let it sit for a couple hours. You're still going to get fuel on you from the filter and the line after the filter, but at least you're not being sprayed. I did it last year in the snow at about 11:00pm with a leatherman and no flashlight. Fun fun!