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Personally i never cared for them much.It seems that they put more leverage on the axle/front spindle. Besides they used to really crack donw on us for haveing our tires out past the fenders, seems that they have relaxed on this lately tho.
They also increase pressure on the wheel studs making them more susceptible to shearing. Best to measure anyway because if you widen the footprint without measuring, you are asking to create rub on front bumpers and outer fenders.
Personally, if you want to widen the truck's footprint, swap wheels for a set with shallower backspacing. Again, you should measure for clearance first.
They do increase leverage on components. But it is no differnt then wider wheels assuming you have the same back spacing. Stud failure is not really an issue if their tight.
As far as scraping goes, you will decrease your turning circle because you dont hit the radius arms. (assuming you reset the stops) Of course you might have to cut fenders/bumper.
As far as handling goes, the wider stance on the back is definatly better. But the wider stance on the front actually moves the center of the tire out from the center of pivot. This causes a kind of bump steer. When you hit a bump on one side of the truck, it tries to drag that tire back. Steering stabilizers help in this reguard.