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Will, First and foremose, Welcome to the Family of Ford Truck Enthusiast. Key assembly needs to be in same position, accessory, as when it was removed. At the end of the key assembly there's a concentric cam that sets into a corrisponding slot inside the ignition switch. Insert the key, which will be in the off position, there's a small ball on the face of the key assembly, use a paperclip, or something simular, depress the ball while rotating the key counterclockwise, this places the assembly in the 'accessory' position and the cam on the key assembly should now be aligned with the slot in the ignition switch, insert the assembly with the key then turn clockwise. Fortunately I don't have to make sense of this pathetic explaination, but if you take a close look at the switch and key assembly hopefully it will make sense.
Don't know why you guys are having issues. To remove a cylinder, you put the key in, turn it to acc. poke a paperclip in the hole, press it, turn the key horizontal and pull it out.
You reverse that move with the exception of the paperclip to re-install the new cylinder. Start with the key teeth pointing towards the door horizontal, poke it in and turn it clockwise. Once it is vertical you can stop, pull the key, or continue turning over to the start position.
If that doesn't get you going, you will have to check a higher paygrade.