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Don't know, as I've not invested in one yet. So far my biggest improvements have been ...
6637 air filter.
New fuel pump .. it was leaking.
bb mod to raise fuel presure.
Clogged MAP sensor hose so turbo would not spool, replaced.
Just the basic stuff. That got me about 3.5 MPG. Just ordered the 3" down pipe and cat delete and should be here next week. Don't expect a hugh gain but should help somewhat with exhaust flow.
Yeah x4 what tj said the big names like superchips and banks are made generically to work on all where these guys test and tuned for each mo done for your truck to get best power and lowest egts.