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My 92 E150 with 250K miles (70K on engine, 10K on rebuilt trans.) will sometimes lurch when there is a small throttle position change at speeds over 40. It did this before the transmission rebuild.
For just a fraction of a second it will buck. It feels like more than a loss of power, that's why I suspected the tranny. Problem is very sporadic. It happens maybe once a week, but it's a little scary. Problem has been present since I bought the van 5 years ago.