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It's an optical illusion. Because of the way the fenders curve around, it makes the tires "look" like they are closer at the top than at the bottom. I have the same thing with my old Dodge 4x4. If it really, really bothers you have a front end place check the alignment. They should do it for free. But if it costs a few bucks its worth the piece of mind!
Is your truck an older bodystyle 250?
Is it 4WD?
If so, there is a front end sagging problem to them.
If it's 2WD, then some tilt in at the top (negative camber) is normal, about .5 to 1 degree.
Normally on Fords, they are set this way to keep the tire wear more even, if there is any positive camber (tilt out at top) the outer edges will shave off really fast.
Twin I beam front ends travel up and down in an arc, which if you ride next to one, you can really see this, plus the wild camber changes as it moves through it's range of motion.
Rezvani's Latest Post-Apocalytic Monster Is a Ford F-150 Raptor Underneath
Slideshow: Called the Fortress, the 850-horsepower pickup combines Raptor underpinnings with military-inspired features, survival equipment, and a starting price of $285,000.