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My truck (2000 F250 7.3 ZF6 supercab long bed xlt) cab is rusted out and dented. Needs cab corners, rockers, doors, fenders, hood but the frame is solid. I'd like to just cab swap it. Ik someone with a clean 2006 cab but it's a crew cab king ranch auto. Ik the wheelbase is different I'll make a custom 7 ft flatbed, but what's the hard part of doing a swap like that? Wiring? Also possibly open to swapping my engine and trans into the newer chassis, but ik the death wobble issue became prominent in 05 and they didn't claim to have fixed it until just a few years ago. Ride quality is better I'm sure, but if that was my only concern I'd go buy a duramax. There's a guy in my area that parts these out and he said it'd be easier to drivetrain swap than cab swap.
I believe the later cabs need a modification to the firewall but don't quote me on that.
I think you'd have a problem putting a crew cab on a supercab frame - I want to say that the way the frame is formed is different and will cause the cab to hit the rails, but don't quote me on that. Regardless I think you'd want to swap with another supercab, it'll make life easier.
As for cab swap vs driveline swap, it's not really any easier to do one over the other, it's just different kinds of work. You're either unhooking everything and pulling the cab to pull the driveline, or unhooking everything, taking the interior out, pulling the cab, and putting a new one back on. About the only thing that makes a driveline swap easier is that you don't really have to get in behind the dash and you don't have to mess with airbags.