6.0 "Bulletproof" line items?
Then, I would say you should do SOME modifications.
Gauges are a must - just in case. They can keep you from having relatively small problems turn into bigger ones. (at a minimum - ECT, EOT, boost, voltage, fuel pressure, and I added a coolant pressure gauge). In fact, I wouldn't buy a used 6.0L without taking my gauges (I can easily hook up everything except the fuel pressure).
Then, assuming a later model year, I would do the following if they haven't already been done:
1. STC fitting on the HPOP
2. Dummy plugs and Stand Pipes
3. I would probably include a new IPR since you are in that far, but it may not be necessary
4. BulletProofDiesel EGR cooler (or EGR delete)
5. This is where the gauges come in handy again - if the oil cooler looks plugged, then install an OEM oil cooler.
6. Blue spring install if needed (again, based on the fuel pressure gauge)
7. FICM upgraded - I prefer Ed at FICMrepair.com
A 140A + alternator would probably be wise.
Be sure to use a quality oil (my preference is certainly 5W40 oil), and use proper filters changed at the proper interval. This includes using the proper coolant.
I would think a mild tow tune would increase your driving pleasure without causing much worry, but I would imagine that opinions will vary on that!
Would you HAVE TO DO the things above on a well cared-for truck? Probably not and certainly not right away, but they would help ensure MANY MANY miles of reliable driving. AGAIN - this is all just personal opinion based on my experiences. Just factor all the spending into the overall value and you will be just fine!
Yes. ^^This is my real point, that getting to 400HP and towing there are two different things. Ford already turned the power up on the 6.0 by over 100HP, they they changed a number of things to get there, but because of that Ford already took out a lot of the headroom for power-added tuning while being able to pull at the max GCWR. Mark kind of buried that point here:
I threw out the 6.7 because if towing at 400HP (or really the 800+lb/ft of torque) is important to you, honestly the 6.7 is a very cost effective way to get there. There's something to be said for the stupid amounts of power the newer trucks have. You can mod up a 6.0 to do that, it'll just never be as reliable with the HP turned up 200% as something that was built to that spec from the start. Add on the fact that the newest 6.0 was installed more than 10 years ago in any F-Series truck, you're stacking paying to mitigate 100k+ miles (only an average of 10k a year for the newest trucks) of unknown use and abuse, plus the performance mods on top of that.
I love the heck out of my truck. I've done a bunch of small things, some of which "add power", but that's never been the goal. The goal has always been to make it pull better, and I have a fully known maintenance history. I could do something like 155cc/30%s with a Powermax, FASS and a big exhaust and up the towing power significantly, but like Dan mentioned I don't need to pass people going up the hill, I would rather get to the top each and every time.
So to take another crack at your original questions:
Gauges! Edge CTS? Had an original Insight CTS and it died. I use Dasboss for iPhone now with Isspro EV2 fuel pressure and EGT gauges. if you want a single integrated box Edge can add both of those, but it costs more.
Engine coolant filter I have one, but honestly if you drop the lower radiator hose and open a block drain and there's not any grit in the bottom of the buckets of coolant, not a 100% necessity.
Engine oil cooler upgrade Stock is fine, some people love the BPD oil-to-air cooler but IMO it's too expensive unless you're always at max load. There's no need to replace it until it fails the TSB test.
EGR upgrade, or EGR delete Like I said before, the new EGR coolers are a problem. Either put in a BPD one (built like the original 03 cooler) or make it go away. Mine mysteriously fell off one winter.
Blue spring mod Not really a mod, if you have low FP you do it. If you don't want to buy an FP gauge.... just do it anyways. It's an update, there are no downsides
Plan on new batteries Upgrade the ground cables, TooManyToys has a thread on it
Plan on new FICM Until it breaks no need to mess with it. Ed at FICMrepair.com is the man when it does
Custom tunes Custom TOW tunes

ARP studs with new OEM gaskets I don't think there's any need to break the engine open until there's a problem. Other people do it preventatively, maybe that's a good idea on a used truck, but I've never wanted to run big power tunes and I know the full history of my truck.... so I'm going to wait. Hopefully a very long time, like until after the body rusts off the frame.
STC, standpipes, dummy plugs If the turbo ever has to come out, do the STC fitting. If you have to go under a valve cover, do that side's rail plug and standpipe. I wouldn't necessarily do them preventatively, but if you pull the turbo for any reason, do the STC fitting.
Turbo cleaning Not a bad idea on a used truck. Also a good excuse for a billet compressor wheel and an excuse to do the STC fitting.
Does this list make sense? What am I missing? Alternator. I've killed two 110A and one 140A alts over two trucks. My wife's Jeep almost caught fire from her 160A stock alt failing, I'm not a fan of pushing those things as hard as the 6.0 does to the stock units, so I bought a big one.
I was truly giving my opinion of what I believed to be a reasonable prediction
of what you were seeking. I was not trying to be a "hater" just honest.
I owned one, my best friend and his son own them as well as many acquaintances that pull campers. There have been some great suggestions given and I wish you all the luck in the world.
Ford Trucks for Ford Truck Enthusiasts










