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Mechanically the A/C compressor is an easy swap. But getting the system clean, dry, leak free and recharging is the challenge. Why are you changing the compressor? Did it fail (and send debris down stream)? Is it working but weak. We do A/C work at my shop. Orifice tubes, reciever/dryers, expansion valves and other parts get replaced when a new compressor goes in depending on system style and how equiped (and the nature of the problem).
Typically, the system is tested for charge. If empty, we pressure it with nitrogen and check for leaks. If system is charged we check low and high side pressures baised on ambient air temp. System gets evactuated and refridgerant stored. Parts get replaced. System has a vacuum pulled for about an hour to get all moisture out and to recheck for leaks. Oil is added (if certain parts are replaced) and a measured charge is put back in. Low and high side pressure inspected and temperature differential checked at inlet and vents.
I've heard the dryer needs to be replaced anytime the compressor is replaced.
Some people swear by this, but I've never replaced one and never had any issues for not doing so. However, if by some chance your system was open to the atmosphere for an extended period of time, or water got into the system; then I would most definitely replace it.
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