See sig...

But seriously, it depends on what you want to do with your truck. A daily-driver/tow-mule would take many of the same mods you see below, minus the large injectors. Stage 1s/2s eventually would be nice, but the below mods as you can afford them would be good. I did them in the order that you see them listed, but I would do trans mods before custom tuning if I were to do it over again...