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Yes, I have one. It is made by A.R.E. Keeps the rain out, not dust tight. Low pressure area in the bed pulls dust, a lot, into the bed through the large joints in the tailgate. Sealed it with a Trailguard seal. Did not hurt, but did not help, my fuel mileage.
Glasstite. See my gallery - it's low profile and I like it a lot. Takes 2 people to put it on/remove it, but it is quick and easy to do. Water tight, locks too.
I've got the ARE hard cover on my S/D, been on the truck since new. I have had no problems with it, it seals good and so far does not leak. I have the bedrug installed in the bed,so that will seal the tailgate up from dust and water. If you will be hauling a lot using the truck bed, it might be a pain to take off and install all the time, as it will take 2 people. In that case a soft cover might be a better choice. As far as fuel mileage, you are keeping airflow out of bed, it might help a little, but not a big improvement!