You're on the right track, you just need to talk to the right person...
Mike Butler at 5-Star tuning knows the V10 and 5.4 engines quite well and has owners singing his praises.
5 Star Tuning | Custom Dynomemeter Chassis Tuning Products and Services
He uses the SCT programming device for his tunes and will teach your truck some new tricks. I don't know personally, but every V10 or 5.4 owner is blown away by how much more he can get out of those engines. Check him out...