I don't want to sway your decision one way or another, just talking from experience. 90% of my driving is empty. I love the 4.30's, but I knew when I ordered it that I was going up in tire size and wanted to be prepared. Plus the thing rips pretty good off the line for a 8,000+lb truck, even w/ the 35" tires...
Just keep reading around this forum and up in the SuperDuty forum, lots of 4.30/3.73 threads.