My 06, 5.4 in a SD 4x4 has 77000 trouble free miles.
I have changed the fuel filter 10 times, tranny fluid and filter 2x Axle fluid 1x, and antifreeze 2x, transfer case 1x. greased my caliper slides more then I can remember. and am still runnin on the original BFG's rotated every 5000.
I enjoy doing maint on my truck
I also opted to have Ford do the plugs at 50,000 miles while it was under warranty because of the known plug issue.