Conversation Between Piolet and Skinny ray

Hey Guy's
I'm New With the 6.0 i got this 06 F250 back in Feb. Last week Radiator started leakin on top blowin coolant all over top of motor so I got my New Mishimoto All Aluminum Radiator today "" is there Any Heads up on Replacing Radiator Things I Should Know or Do Besides Flushing the System before I install New Radiator ??