I really like the zoodad mod for earlier F250's. But my 2008 F250 with 5.4 v8, the intake goes out the side to the fender well rather than out the front, so it doesn't work for me. What ideas are there for the 2008 like mine to open up the intake.

I'm talking DIY intakes here, not buying a CAI

 

Do a search (either here or on your search engine of choice) for the Gott's airbox modification.

Basically you take the horn that goes through the fender wall off, take a 4" piece of ABS and sand it to fit through the hole in the fender well. Then use a 4" flexible pipe coupling to attach it to the filter bell.

I did it on an F150 I owned, it worked great!