Good question. IIRC, I've read a couple of posts on here from folks who made the switch from the 6.0. I am interested as well so thanks for asking.....I'll be watching for responses. In the meantime, here's one you may or may not have read from a former 6.4 owner who switched.
https://www.ford-trucks.com/forums/1...-to-6-2-a.html