I would say once you have all the air out, do it a couple more tires for good measure (it can't hurt). The last couple times, I usually have the person helping me push the pedal extra hard to push the fluid out with velocity, just in case there is a pesky bubble caught up on something.

I do my breaks in the order LazyK mentioned above, because that's how everyone says to do it, but I never understood why. Anyone have some insight on that?