pretty much trouble free really on these models. they've been around essentially since 2003 with minor skin/motor/tranny changes. Ford has really got these dialed in for the most part IMO.

check the hood for bubbling and the other body panels for the same (aluminum corrosion). otherwise just check the normal stuff. hopefully you've read about the 5.4 3v sparkplugs sticking issue. not a deal killer, but can be an annoyance