My wife and I both like the looks and room of the Flex. Recently purchased an '09 Flex Limited to replace our '97 Expedition. The wife is the primary driver (90%+). The Edge didn't have adequate interior room for me (6'6"), while the Flex is even roomy in the middle seat.
We have noticed the "love it or hate it" appeal of the Flex, never noticed the guy / gal thing. The "station wagon thing" was part of the appeal of the Flex. For the most part we have had wagons for the past 35+ years as they seem to better fit our lifestyle.
We opted for the Towing package on the Flex, cause sometimes I just dont need the F-250. With a 4500# trailer capacity, the Flex should do just fine.

Roger Carter