pretty much nothing, but driving it smartly and keeping the maintenance up
you can get it some custom programming for the ECM. Will run you about $500. It will give you way better HP/TQ gains, and you should see MPG gains if you keep your foot out of it.
but $500 for a tiny MPG gain isn't economical...unless of course you want the performance gains, and the MPG's is how you justify it to the wife.