The M-E-L engines were used from July 1958 thru the end of the 1967 model run.
There is no such thing as an M-E-L engine prior to July 1958, because there was no such thing as M-E-L.
The 1958 Edsel had its own division prior to July. Because of poor sales, the Edsel Division was folded into the Lincoln/Mercury Division forming M-E-L.
The largest M-E-L engine is a 462, which was used in 1966/67 Lincoln's. The 430 was last used in 1965.