Properly processed bio is perfectly fine in our engines. There are no modifications needed. One thing to note: bio is a solvent and will clean out leftover gunk in your fuel tank and lines. Keep a spare fuel filter handy, you might have to replace it soon as the bio cleans out your fuel system.
I wish there was a bio station close by. I used to run bio-diesel when I lived in SC, and my truck ran so much better on that stuff.