You should be able to shift your 460 at 2500 rpm or so and be just fine. 4000 if you're in a big hurry. Don't go past 4500.

Is this a 4 wheel drive truck?

A throwout bearing requires removal of the transmission. If 4WD, sometimes the transfer case must be moved or removed as well.

This is not terribly difficult in a shop with proper tools, overhead lifts, transmission jacks etc, but it does take time. (at up to $90 per hour or more shop time charge)

Doing this job on the driveway could prove fatal to an inexperienced first timer.

As for the clutch, whenever a transmission is removed from a vehicle, unless the clutch is known to be fairly new, you replace the clutch and pressure plate and resurface the flywheel if needed. These parts, while not free, are fairly inexpensive compared to the labor of transmission r & r.

You may wish to get a couple of quotes and be sure to check the shop out--BBB, friends who have been there, etc. You do not want a shop that says "Well, we've never done a 460 in an F350, but we can do it. I think."

Good luck and post any results, quotes, questions, and our team of experts and internet addicts will provide addition suggestions and information.