You're thinking methanol. E85 is a lot more forgiving. I would replace all the rubber lines with new ones though. They sell rubber fuel line at Napa that I used on my truck when I converted it to E85. It's their fuel injection hose. It says "multi-fuel compatibility" on the side of it. Probably the regular stuff would have worked, but why take the chance?
I'd also get a new fuel pump or rebuild your old one.
I had been running E10 for years in the old tank in the '70 F100. After a while it cleaned out some gunk that clogged the fuel filter. I expect the E85 to clean out a bit more gunk. Again, no big deal.