far as I know once you apply the tune, you no longer need the tuner attached, unless u want to use it as a monitor.
least that is the way all the tuners I have ever used worked, including the spartan on my 08 f350.
1955 F100 460/c6, 3.55ls - 436 hp, 489 tq
2012 F350 4x4, DRW, 3.73ls, CC, LB, 400 hp, 800 tq
2013 Keystone Alpine 3720FB 5th wheel. 40', 15,500gvwr