200K on my 2003 Expedition 5.4L
I have no money to buy another so I have to keep this one going. Oil and filter every 5K. Coolant and trans flush and new fuel filter every 50 K.
New plugs, cops and serpentine belt every 100K. Major problem was limited slip differential stopped slipping when turning from a complete stop. Ford rebuilt it. The clutch pack and friction modifiers had to be corrected and had to have a new ring gear. That was about $2K (of course it was out of warranty). It has been fine ever since. The vacuum hoses do get brittle and Ford has some neat little plastic vacum line pieces that can be discarded and bypassed with a plain old vacuum line circled around to make the bend. Ford designed a nice plastic cover to go over the intake and make the engine compartment look pretty. Snapping it on and off interferes with some of the vacuum lines so I have removed it and it is in the attic.