Gentlemen, perhaps you can give me some advice?

I'm looking for a replacement for our '76 F250 with the 460 (2wd). It is becoming difficult to keep it running since it sits for 10 months and then is expected to run well on an isolated, wet island on the coast.

Which years, engines, models do you recommend for the most reliable but easy to service Ford pickup. I don't need the 460 but must admit it runs well once you get it started. Would like a 4wd. Should I stay away from FI?

Thanks!