Hey Cheeto, how ya been? Your sig might be enough to get Dave S to show up around these parts again lol.

As for the 2wd pickup on snow/ice I'd say you'll definitely run into trouble from time to time. You'll want some weight in the back and you'll want some good snow tires, maybe even studs. Also buy a set of tire chains and keep 'em in the truck in case you get buried up somewhere. If you have a limited slip or locking rear end you'll really have your hands full at times on snow/ice.

It might be a good idea to pick up an old/cheap 4x4 of some sort for winters up here.

It is worth noting that I'm speaking for the winters we have on the eastern side of WV in the mountains. Not sure how bad they get in the upper panhandle.