ecoboost twin turbo v6- lighter, higher torque rating, flatter torque curve, about 2-3mpg better combined average, and a tuner away from an extra 50hp 100ft/lbs torque (dont say turbos add complications to break all those big diesels you see in dump trucks to semis are TURBO diesels as are most all modern diesels).
5.0- most advanced v8 ford has made solid naturally aspirated type motor strong and good mpg makes plenty of power to do most you would want to do with an F150