(quote I am new to this site and have been looking on the internet for a while and was wondering, besides being spark plugs and wires and/or a bad coil pack, what other things could make it so i have misfires on cylinders 4 and 6? going to replace the plugs and wires later today when they get to my house but i just want to know what other things i could be so i can evaluate the potential repair cost and should the wires for cylinders 4,5, and 6 be under or over the intake manifold? i bought my truck used and they are currently under the manifold i think it would make more sense to have them over personally.

I have a 1997 Ranger 4WD with the 6 cylinder 4.0L engine quote)

Welcome to FTE.

A number of things can cause a cyl misfire. Most autoparts stores will scan the computer for trouble codes at no cost if the CEL is lit, so post All code Numbers found as they can provide good trouble shooting clues.

You'll want to find the root cause & put it right without delay, as the cat converter has to process the unburned fuel & that can overheat & fatally damage it internaly.