Not really, none that I have heard of. 80k in 2+ yrs is puttin' some miles on it now, how much they asking? I'm driving an 05 F250 5.4 work truck right now that will turn 169k tomorrow, and I see it has a new exhaust manifold and alternator. The rest looks dirty like it hasn't been apart and it still runs good. Not sure if thats still the 2 valve? Probably is, but the superintendent I'm working for has an 09 5.4 with 110k on it and no issues that I know of. Spark plug issue was resolved in 06 or 07 maybe? HTH