Easiest way is to place a front drive axle on 4x4 leaf springs and lift the rear springs. Add a modern motor and trans/T-case on custom mounts and some drive shafts.
Adding a new fame would not give you any benefits over the frame you all ready have. The frame width is basically the same from 61 to 96. You can use a 44 from a 250 up to 77.5 and convert the hubs over to five lug. A F100 axle 66 and up will be a coil spring type and not conductive to a leaf spring swap.
Garbz
Garbz