It will not hurt the engine if properly maintained. These were designed to run at higher RPM's than the old V8's.

With the additional torque of V10, you can get away with lower (numerically) gears and keep the same performance.

My advice: If you are happy with current performance, use the calculators above to find out what gears keep the rpm the same at a given speed, and then go one ratio deeper (numerically higher) to make up for the loss in performance due to the (much) heavier tires. If using wide or really burly tires (like swampers), these add a LOT more weight so go two ratios deeper. adding rotating mass really kills performance, so you want a lot more power or gear advantage.