How much horse power do you actually intend to have?

I built a 521 blackbird motor years ago "a Cad 500 with an offset ground crank".

Well I put a stiff roller cam, roller rockers, ported heads, 9.7-1 compression, and matched dual plane manifold. I dutifully installed it into a road raced preped 69 Nova, and I thought I was going to die. This was with 2.73 gears, and a RV torque convertor behind it. Drag radials couldn't keep it planted, and I was fast enough to get kicked off 1/4 tracks.

So I can only imagine what Kasse heads, and forced induction would do on such a big motor. You better get right with the God of your choice, and I would try 2 or 3 to be on the safe side.