2010 F250 6.8l crew cab v10 4x4 Gas mileage
 

Recently purchased my ford and it looks like I am getting only 8-10 mpg around town. What can I do to get more mpg or is this what I should expect? Only on my second tank of gas. My vehicle has 4900 miles and has 325/60 18 tires.

8-10 MPG is typical of a V10. There is very little you can do to improve that other than lighten your foot. A tuner may help, but dont count on it.