Yes, the fuel pump is going out.
I had this exact problem a few years ago.
Running around town, no problem, out on the road, after 60-70 miles, the pump would get like "heat soaked" and shut down, let the van sit for 20 minutes and all was fine, until the next unscheduled rest stop
I ended up buying a fuel pump/sending unit from the Ford truck dealer, and it turned into a "bad" pump from day one, until I got stranded 4 states from home, and had a Napa pump installed, and got my $$$ back from the 1 year warranty from Ford.
But over the years, every 6-8 months the van will skip a beat, and this is the time I drop the 40 gallon tank (try to get it as empty as possible) and clean the sock filter, and the inter filter, and even replace them in the pass. The pump sending unit mounts from the top, and I've even replace the O-ring, but fine grit from the road gets into the tank, and plugs up the filters, once clean, the van runs for another 8 months or so until its filter cleaning time.
I'm telling you all this, cause, it's better to drop the tank first, and check for any "debris" in the sock filters before you run out and buy a new fuel pump, Don't know about your, but the pump for a cut-away cube van costs $325+.