I know every
engine has a degree of blow by, thus the reason for a PCV system. I havent made it a practice to compare blow by between engines by removing the oil cap and with the sophistication of today's engines Im not entirely sure that is an accurate measure of "blow by". These new engines are designed to burn and reburn in the name of emissions. On a gas
engine I know crankcrase pressure (which is really what you are experiencing by removing the oil cap) can be altered by the size of the camshaft, the amount of vacuum, whether you run a breather or a PCV system, etc, etc.
I think if you have a true blow by issue on your 6.4 you will experience low boost and/or poor performance. As your boost builds your blow by would get worse and at full boost your crankcrase pressure would be so great that you would be ingesting oil in to the system and probably smoking.
One of the performance tricks on 7.3's and 6.0's is to re-route the blow by tube to the rear of the truck rather than it being fed back in to your intake. I believe there are more in depth threads on this in the tech section of both the 7.3 and 6.0 forums that might provide you with more details pertaining to your concern.