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well, its not quite that bad. The "original" spark plugs were two piece in 2005- 2006 ( possibly 2007?) and some snap in half during removal. You need a special tool to get those broken parts out.. If your plugs were changed at 100K miles and you have the newer style plugs, that should not happen. The plugs are buried under the COPS and several items need to be removed for access. 6 hours would assume you ran into some problems.
Changed plugs and fuel filter today it runs even worse now?
Looking at plugged CAT's tomorrow , then after that who knows?
Maybe weak fuel pump , no way to test pressure.