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If its a 2wd you probably have 3:08 or maybe3:55 gearing. Your gunna loose a lot of power if its the 3:08 with 33's I know my 3:55 with 33's had quite the power loss. Still drivable with 33's and 3:55 but don't plan on towing anything.
You will not need more than a leveling kit, but you wont like it very long without a real lift.You will have to space the front bumper out as well as accept a much larger turning radius due to rubbing if they are wide in any way. Here is my truck, a 4WD that sits higher from the factory, with a 4 inch lift on 33's:
Looking at that you can probably figure what your truck will look like sitting 4 inches lower... I wouldn't recommend it.
As far as gearing goes, I have 3.55's as well. Like Midnight said, they aren't too bad until you throw a load behind it.
Well, it depends on if you have your heart set on the 33's. If you dont mind downsizing, i had a set of 31's on my truck. no lift, nothing, just put em on n go. but i will say a leveling kit would make it look nicer.
I also have 3.55 gears and it is a pain in reverse and first gear. I have to slip the clutch quite a bit. But overall its driveable and on some hills i have to downshift